Chicken Alfredo Lasagna Roll-ups (Dairy, Egg, Soy, Gluten, Nut Free)

A Cozy, Allergy-Friendly Twist on a Classic

Lasagna has always been a comfort food staple in my home. But when my family faced multiple food allergies, I had to rethink our favorite dishes. That’s how I discovered these Chicken Alfredo Lasagna Roll-Ups. They’re creamy, flavorful, and free from dairy, eggs, soy, gluten, and nuts. Perfect for those with dietary restrictions, yet so delicious that everyone at the table enjoys them.

The concept is simple: tender lasagna noodles rolled around a savory chicken filling, smothered in a rich, dairy-free Alfredo sauce, and baked to perfection. It’s a dish that brings warmth and satisfaction, without the allergens.

Ingredients and Substitutions

Here’s what you’ll need:

For the Alfredo sauce:

• ½ cup vegan butter or homemade alternative
• 8 oz non-dairy cream cheese or canned coconut cream
• 1 cup plain non-dairy yogurt
• 1 tsp salt
• ¼ tsp pepper
• ½ tsp onion powder
• 2 tsp minced garlic
• 1 tsp Italian seasoning
• 5 tbsp cornstarch or arrowroot mixed with ½ cup cold non-dairy milk
• 1½ cups additional non-dairy milk

For the roll-ups:

• 12–14 dry gluten-free lasagna noodles
• 4 cups shredded rotisserie chicken
• 2 cups vegan mozzarella or cheddar shreds, divided
• ½ cup freshly grated vegan Parmesan cheese, divided
• 1 tsp garlic powder
• ½ tsp Italian seasoning
• Chopped fresh parsley for garnish (optional)

Substitutions:

• If avoiding legumes, opt for canned coconut cream instead of non-dairy cream cheese.
• Arrowroot powder can replace cornstarch for thickening.
• Use your favorite non-dairy milk, such as oat or rice milk, ensuring it’s free from allergens.

Step-by-Step Instructions

1. Prepare the sauce: In a saucepan, combine vegan butter, non-dairy cream cheese, yogurt, salt, pepper, onion powder, garlic, and Italian seasoning. Heat over medium until smooth. Mix cornstarch or arrowroot with cold non-dairy milk, then add to the sauce along with the additional milk. Stir until thickened. Set aside.
2. Preheat oven: Set your oven to 350°F (175°C). Lightly grease a 9×13-inch baking dish and spread a thin layer of Alfredo sauce on the bottom.
3. Cook noodles: Boil lasagna noodles according to package instructions until al dente. Drain and rinse with cold water to prevent sticking.
4. Prepare filling: In a large bowl, mix half of the Alfredo sauce with shredded chicken, ½ cup vegan mozzarella, ¼ cup vegan Parmesan, garlic powder, lemon zest, and Italian seasoning.
5. Assemble roll-ups: Lay noodles flat on a clean surface. Pat dry with paper towels. Spread the chicken mixture evenly over each noodle, then roll up tightly. Place seam-side down in the prepared baking dish.
6. Add sauce and cheese: Pour the remaining Alfredo sauce over the roll-ups. Sprinkle with the remaining vegan mozzarella and Parmesan cheeses.
7. Bake: Cover the dish with aluminum foil and bake for 20 minutes. Remove the foil and bake for an additional 10 minutes, or until the cheese is melted and bubbly.
8. Optional broil: For a golden top, broil for 2–3 minutes at the end of baking.
9. Serve: Garnish with chopped fresh parsley if desired. Serve warm and enjoy.

Frequently Asked Questions

Can I make this dish ahead of time?
Yes, you can assemble the roll-ups and refrigerate them for up to 24 hours before baking. Add a few extra minutes to the baking time if cooking from cold.

Can I freeze the roll-ups?
Absolutely. Assemble the dish, cover tightly, and freeze for up to 2 months. Thaw in the refrigerator overnight before baking.

What can I use instead of rotisserie chicken?
Cooked and shredded chicken breasts or thighs work well. For a vegetarian option, consider using sautéed mushrooms or a plant-based chicken substitute.

Is there a substitute for vegan Parmesan?
You can use nutritional yeast for a cheesy flavor or omit it altogether if preferred.

Can I use a different type of pasta?
While lasagna noodles are traditional, you can experiment with other gluten-free pasta shapes, adjusting the assembly accordingly.

This Chicken Alfredo Lasagna Roll-Up recipe has become a beloved meal in our household. It’s comforting, satisfying, and inclusive for those with food allergies. I hope it brings the same joy to your table.

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